7rdl

X-ray diffraction
2.71Å resolution

Crystal structure of PCDN-22A, an anti-HIV antibody from the PCDN bnAb lineage

Released:
Source organism: Homo sapiens
Entry authors: Omorodion O, Wilson IA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
PCDN-22A Fab light chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 216 amino acids
Theoretical weight: 23.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PCDN-22A Fab heavy chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 232 amino acids
Theoretical weight: 24.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 70.079Å b: 105.471Å c: 145.926Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.23 0.258
Expression system: Homo sapiens