7r52

X-ray diffraction
2.94Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192550 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Toll-like receptor 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 807 amino acids
Theoretical weight: 92.31 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q9NR97 (Residues: 27-827; Coverage: 79%)
Gene names: TLR8, UNQ249/PRO286
Sequence domains: Leucine rich repeat

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 162.537Å b: 87.227Å c: 153.054Å
α: 90° β: 120.1° γ: 90°
R-values:
R R work R free
0.254 0.253 0.274
Expression system: Drosophila melanogaster