7qu2

X-ray diffraction
2.5Å resolution

Junin virus GP1 glycoprotein in complex with Fab fragment of antibody JUN1

Released:
Entry authors: Ng WM, Sahin M, Krumm SA, Seow J, Zeltina A, Harlos K, Paesen G, Pinschewer DD, Doores KJ, Bowden TA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Fab JUN1 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 26.4 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Fab JUN1 light chain Chain: B
Molecule details ›
Chain: B
Length: 217 amino acids
Theoretical weight: 23.94 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Glycoprotein G1 Chain: C
Molecule details ›
Chain: C
Length: 156 amino acids
Theoretical weight: 18.1 KDa
Source organism: Argentinian mammarenavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: C1K9J9 (Residues: 87-232; Coverage: 30%)
Gene name: GPC
Sequence domains: Arenavirus glycoprotein

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 69.847Å b: 66.752Å c: 73.101Å
α: 90° β: 103.5° γ: 90°
R-values:
R R work R free
0.225 0.223 0.254
Expression system: Homo sapiens