X-ray diffraction
1.9Å resolution

Crystal structure of homing endonuclease-associated TliVMA intein (C1A, d333-339)

Source organism: Thermococcus litoralis
Primary publication:
Structural Basis for the Propagation of Homing Endonuclease-Associated Inteins.
Front Mol Biosci 9 855511 (2022)
PMID: 35372505

Function and Biology Details

Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
V-type ATP synthase alpha chain Chain: A
Molecule details ›
Chain: A
Length: 374 amino acids
Theoretical weight: 42.27 KDa
Source organism: Thermococcus litoralis
Expression system: Escherichia coli
  • Canonical: H3ZKG9 (Residues: 235-666; Coverage: 37%)
Gene names: OCC_09254, atpA
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 69.57Å b: 43.96Å c: 72.12Å
α: 90° β: 104.62° γ: 90°
R R work R free
0.178 0.176 0.21
Expression system: Escherichia coli