X-ray diffraction
2.43Å resolution

Crystal structure of MYORG bound to 1-deoxygalactonojirimycin

Source organism: Homo sapiens
Entry authors: Meek RW, Davies GJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Myogenesis-regulating glycosidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 636 amino acids
Theoretical weight: 72.46 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
  • Canonical: Q6NSJ0 (Residues: 80-714; Coverage: 89%)
Gene names: KIAA1161, MYORG
Sequence domains: Glycosyl hydrolases family 31

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, FUC
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P1
Unit cell:
a: 73.113Å b: 78.882Å c: 176.221Å
α: 80.777° β: 80.209° γ: 62.641°
R R work R free
0.225 0.224 0.25
Expression system: Trichoplusia ni