› 7qp0

X-ray diffraction
1.6Å resolution

Crystal structure of metacaspase from candida glabrata with magnesium

Released:
DOI: 10.2210/pdb7qp0/pdb
PDB entry 7qp0 coloured by chain, front view.
PDB entry 7qp0 coloured by chain, side view.
PDB entry 7qp0 coloured by chain, top view.
Source organism: [Candida] glabrata
Primary publication:
Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium.
Conchou L, Doumèche B, Galisson F, Violot S, Dugelay C, Diesis E, Page A, Bienvenu AL, Picot S, Aghajari N, Ballut L
Commun Biol 5 1158 (2022)
PMID: 36316540

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179622 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metacaspase-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 392 amino acids
Theoretical weight: 43.84 KDa
Source organism: [Candida] glabrata
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6FPX9 (Residues: 1-392; Coverage: 100%)
Gene names: CAGL0I10945g, MCA1
Sequence domains: Caspase domain

Ligands and Environments

2 bound ligands:
Ligand EPE 2 x EPE
Ligand MG 6 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2
Unit cell:
a: 95.7Å b: 83.6Å c: 87.8Å
α: 90° β: 106.6° γ: 90°
R-values:
R R work R free
0.177 0.175 0.202
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Insights on Novel Effectors and Characterization of Metacaspase (RS107_6) as a Potential Cell Death-Inducing Protein in Rhizoctonia solani.
Kavya et al. (2023)

1 mention without citation

Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium.
Conchou et al. (2022)