› 7q5d

X-ray diffraction
1.8Å resolution

Structure of EPCR in a non-canonical conformation

Released:
DOI: 10.2210/pdb7q5d/pdb
PDB entry 7q5d coloured by chain, front view.
PDB entry 7q5d coloured by chain, side view.
PDB entry 7q5d coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of EPCR in a non-canonical conformation
Erausquin E, Rodriguez-Fernandez A, Lopez-Sagaseta J
Biorxiv (2021)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194000 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Endothelial protein C receptor Chain: A
Molecule details ›
Chain: A
Length: 195 amino acids
Theoretical weight: 22.2 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UNN8 (Residues: 18-210; Coverage: 87%)
Gene names: EPCR, PROCR
Sequence domains: MHC-I family domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand CYS 1 x CYS
Ligand PTY 1 x PTY
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P3121
Unit cell:
a: 70.47Å b: 70.47Å c: 96.635Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.184 0.184 0.195
Expression system: Spodoptera frugiperda

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