› 7pa9

X-ray diffraction
2.75Å resolution

JC polyomavirus VP1 in complex with Fab 98D3

Released:
DOI: 10.2210/pdb7pa9/pdb
PDB entry 7pa9 coloured by chain, front view.
PDB entry 7pa9 coloured by chain, side view.
PDB entry 7pa9 coloured by chain, top view.
Source organisms:
Entry authors: Stroeh LJ, Harprecht C, Freytag J, Stehle T

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225019 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Major capsid protein VP1 Chains: AAA, BBB, CCC, DDD, EEE, FFF, GGG, HHH, III, JJJ
Molecule details ›
Chains: AAA, BBB, CCC, DDD, EEE, FFF, GGG, HHH, III, JJJ
Length: 272 amino acids
Theoretical weight: 30.08 KDa
Source organism: JC polyomavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03089 (Residues: 23-290; Coverage: 76%)
Sequence domains: Polyomavirus coat protein
Fab 98D3 VH Chains: KKK, MMM, OOO, QQQ, TTT, VVV, XXX, YYY, bbb, ccc
Molecule details ›
Chains: KKK, MMM, OOO, QQQ, TTT, VVV, XXX, YYY, bbb, ccc
Length: 404 amino acids
Theoretical weight: 43.94 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Fab 98D3 VL Chains: LLL, NNN, PPP, RRR, SSS, UUU, WWW, ZZZ, aaa, ddd
Molecule details ›
Chains: LLL, NNN, PPP, RRR, SSS, UUU, WWW, ZZZ, aaa, ddd
Length: 212 amino acids
Theoretical weight: 23.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 170.97Å b: 202.31Å c: 251.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.207 0.263
Expression systems:
  • Escherichia coli
  • Homo sapiens

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