X-ray diffraction
2.28Å resolution

Crystal structure of the KDEL receptor bound to HDEF peptide at pH 6.0

Source organisms:
Entry authors: Newstead S, Parker JL

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ER lumen protein-retaining receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 24.48 KDa
Source organism: Gallus gallus
Expression system: Saccharomyces cerevisiae
  • Canonical: Q5ZKX9 (Residues: 1-212; Coverage: 100%)
Gene names: KDELR2, RCJMB04_8l23
Sequence domains: ER lumen protein retaining receptor
Molecule details ›
Chain: B
Length: 7 amino acids
Theoretical weight: 849 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P21
Unit cell:
a: 47.383Å b: 37.533Å c: 62.685Å
α: 90° β: 95.22° γ: 90°
R R work R free
0.247 0.245 0.288
Expression systems:
  • Saccharomyces cerevisiae
  • Not provided