X-ray diffraction
1.59Å resolution

Crystal structure of IpgC in complex with a follow-up compound based on J20

Source organism: Shigella flexneri
Entry authors: Gardonyi M, Heine A, Klebe G

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Chaperone protein IpgC Chains: A, B
Molecule details ›
Chains: A, B
Length: 143 amino acids
Theoretical weight: 16.31 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P0A2U4 (Residues: 10-151; Coverage: 92%)
Gene names: CP0129, ipgC, ippI
Sequence domains: Tetratricopeptide repeat

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P3221
Unit cell:
a: 57.788Å b: 57.788Å c: 160.301Å
α: 90° β: 90° γ: 120°
R R work R free
0.19 0.188 0.22
Expression system: Escherichia coli BL21(DE3)