› 7obp

X-ray diffraction
1.8Å resolution

Crystal structure of the human NCOA7-AS TLDc domain

Released:
DOI: 10.2210/pdb7obp/pdb
PDB entry 7obp coloured by chain, front view.
PDB entry 7obp coloured by chain, side view.
PDB entry 7obp coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the TLDc domain of human NCOA7-AS.
Arnaud-Arnould M, Tauziet M, Moncorgé O, Goujon C, Blaise M
Acta Crystallogr F Struct Biol Commun 77 230-237 (2021)
PMID: 34341188

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185563 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear receptor coactivator 7 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 168 amino acids
Theoretical weight: 19.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8NI08 (Residues: 777-942; Coverage: 18%)
Gene names: ERAP140, ESNA1, NCOA7, Nbla00052, Nbla10993
Sequence domains: TLD

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P212121
Unit cell:
a: 68.41Å b: 107.06Å c: 146.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.177 0.221
Expression system: Escherichia coli BL21(DE3)

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Citations

3 mentions without citation

Oxidative stress protein Oxr1 promotes V-ATPase holoenzyme disassembly in catalytic activity-independent manner.
Khan et al. (2022)
2 more