7o4b

X-ray diffraction
2.59Å resolution

Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with penicillin G

Released:
Entry authors: Martinez Caballero S, Hermoso JA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PASTA domain-containing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 650 amino acids
Theoretical weight: 72.36 KDa
Source organism: Staphylococcus aureus subsp. aureus COL
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H2WVW5 (Residues: 65-713; Coverage: 87%)
Gene names: SACOL1194, pbp1
Sequence domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P6422
Unit cell:
a: 180.649Å b: 180.649Å c: 223.466Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.205 0.242
Expression system: Escherichia coli BL21(DE3)