› 7o0b

X-ray diffraction
2.13Å resolution

TRIM3 Filamin domain

Released:
DOI: 10.2210/pdb7o0b/pdb
PDB entry 7o0b coloured by chain, front view.
PDB entry 7o0b coloured by chain, side view.
PDB entry 7o0b coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Williams FP, Yikilmazsoy A, Hennig J

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130936 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tripartite motif-containing protein 3 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 11.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75382 (Residues: 318-420; Coverage: 14%)
Gene names: BERP, RNF22, RNF97, TRIM3
Sequence domains: Filamin/ABP280 repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: C2
Unit cell:
a: 56.017Å b: 33.504Å c: 58.844Å
α: 90° β: 117.253° γ: 90°
R-values:
R R work R free
0.228 0.227 0.258
Expression system: Escherichia coli BL21(DE3)

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