› 7nni

X-ray diffraction
1.54Å resolution

Function and Biology Details

Reaction catalysed: 
N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = N-acetyl-L-glutamyl 5-phosphate + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162037 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-acetyl-gamma-glutamyl-phosphate reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 354 amino acids
Theoretical weight: 36.49 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WPZ9 (Residues: 1-352; Coverage: 100%)
Gene names: MTCY06H11.17, Rv1652, argC
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2
Unit cell:
a: 140.688Å b: 77.991Å c: 88.292Å
α: 90° β: 127.52° γ: 90°
R-values:
R R work R free
0.186 0.185 0.208
Expression system: Escherichia coli BL21(DE3)

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