7nml

X-ray diffraction
1.43Å resolution

Galectin-1 in complex with 4-Amino-6-chloro-1,3-benzenedisulfonamide

Released:
Source organism: Homo sapiens
Entry authors: Grimm C, Bechold J, Seibel J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 43.319Å b: 58.475Å c: 112.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.176 0.211
Expression system: Escherichia coli