7ngp

Electron Microscopy
15Å resolution

D1-state of wild type human mitochondrial LONP1 protease

Released:
Source organism: Homo sapiens
Entry authors: Mohammed I, Schmitz KA, Schenck N, Maier T, Abrahams JP
Related structures: EMD-12316

Function and Biology Details

Reaction catalysed:
Hydrolysis of proteins in presence of ATP.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lon protease homolog, mitochondrial Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 826 amino acids
Theoretical weight: 93.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P36776 (Residues: 123-948; Coverage: 86%)
Gene names: LONP1, PRSS15
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 15Å
Relevant EMDB volumes: EMD-12316
Expression system: Escherichia coli BL21(DE3)