X-ray diffraction
1.67Å resolution

Crystal structure of alpha Carbonic anhydrase from Schistoso ma mansoni bound to 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]selenourea


Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Carbonic anhydrase Chains: A, B
Molecule details ›
Chains: A, B
Length: 332 amino acids
Theoretical weight: 37.93 KDa
Source organism: Schistosoma mansoni
Expression system: Cricetulus griseus
  • Canonical: A0A3Q0KSG2 (Residues: 21-298; Coverage: 92%)
Sequence domains: Eukaryotic-type carbonic anhydrase

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 11.2C
Spacegroup: P3221
Unit cell:
a: 103.279Å b: 103.279Å c: 132.799Å
α: 90° β: 90° γ: 120°
R R work R free
0.179 0.178 0.205
Expression system: Cricetulus griseus