7mto

X-ray diffraction
1.79Å resolution

Crystal Structure of SET/I2PP2A/TAF-1Beta core

Released:
Source organism: Homo sapiens
Entry authors: Roth BM, DePalma RM, Ogretmen B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein SET Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 24.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01105 (Residues: 37-238; Coverage: 70%)
  • Best match: Q01105-2 (Residues: 23-225)
Gene name: SET
Sequence domains: Nucleosome assembly protein (NAP)

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Unit cell:
a: 53.713Å b: 55.275Å c: 79.934Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.189 0.239
Expression system: Escherichia coli BL21(DE3)