7mt1

X-ray diffraction
1.3Å resolution

Crystal structure of Human Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1)

Released:
Source organism: Homo sapiens
Entry authors: Hutchinson A, Seitova A, Dong A, Loppnau P, Edwards AM, Arrowsmith CH, Halabelian L, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-154939 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Platelet-activating factor acetylhydrolase IB subunit beta Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 39.01 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P43034 (Residues: 86-410; Coverage: 79%)
Gene names: LIS1, MDCR, MDS, PAFAH1B1, PAFAHA
Sequence domains: WD domain, G-beta repeat

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 36.728Å b: 68.572Å c: 69.549Å
α: 90° β: 101.28° γ: 90°
R-values:
R R work R free
0.178 0.177 0.197
Expression system: Spodoptera frugiperda