7mru

X-ray diffraction
1.33Å resolution

Function and Biology Details

Reaction catalysed:
D-dopachrome = 5,6-dihydroxyindole + CO(2)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-dopachrome decarboxylase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 117 amino acids
Theoretical weight: 12.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P30046 (Residues: 2-118; Coverage: 99%)
Gene name: DDT
Sequence domains: Macrophage migration inhibitory factor (MIF)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 40.748Å b: 75.891Å c: 103.862Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.161 0.18
Expression system: Escherichia coli