X-ray diffraction
1.55Å resolution

Crystal Structure of the ZnF4 of Nucleoporin NUP153 in complex with Ran-GDP

Source organisms:
Entry authors: Bley CJ, Nie S, Mobbs GW, Petrovic S, Gres AT, Liu X, Mukherjee S, Harvey S, Huber FM, Lin DH, Brown B, Tang AW, Rundlet EJ, Correia AR, Chen S, Regmi SG, Stevens TA, Jette CA, Dasso M, Patke A, Palazzo AF, Kossiakoff AA, Hoelz A

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GTP-binding nuclear protein Ran Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 24.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P62826 (Residues: 1-216; Coverage: 100%)
Gene names: ARA24, OK/SW-cl.81, RAN
Sequence domains: Ras family
Nuclear pore complex protein Nup153 Chain: B
Molecule details ›
Chain: B
Length: 42 amino acids
Theoretical weight: 4.46 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
  • Canonical: P49791 (Residues: 838-874; Coverage: 3%)
Gene name: Nup153
Sequence domains: Zn-finger in Ran binding protein and others

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21212
Unit cell:
a: 59.78Å b: 80.11Å c: 54.48Å
α: 90° β: 90° γ: 90°
R R work R free
0.163 0.162 0.19
Expression system: Escherichia coli