7mju

X-ray diffraction
2.1Å resolution

Crystal structure of human AF10 PZP bound to histone H3 tail

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone H3.1; Protein AF-10 Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 22.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P68431 (Residues: 2-14; Coverage: 10%)
  • Canonical: P55197 (Residues: 19-208; Coverage: 18%)
Gene names: AF10, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, MLLT10
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 42.92Å b: 54.33Å c: 47.78Å
α: 90° β: 106.82° γ: 90°
R-values:
R R work R free
0.167 0.165 0.206
Expression system: Escherichia coli K-12