7m6d

X-ray diffraction
3.1Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-209826 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (6 distinct):
CR3022 Fab Heavy Chain Chain: A
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 23.8 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
CR3022 Fab Light Chain Chain: B
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 24.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 212 amino acids
Theoretical weight: 24 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 328-533; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
BG4-25 Fab Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 224 amino acids
Theoretical weight: 23.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
BG4-25 Fab Light Chain Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 56.023Å b: 104.324Å c: 268.784Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.218 0.259
Expression system: Homo sapiens