7ly1

X-ray diffraction
2.2Å resolution

Crystal structure of Pseudomonas aeruginosa PBP3 in complex with vaborbactam

Released:

Function and Biology Details

Reaction catalysed:
Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidoglycan D,D-transpeptidase FtsI Chain: A

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS-II BEAMLINE 17-ID-1
Spacegroup: P212121
Unit cell:
a: 68.095Å b: 83.502Å c: 88.419Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.241
Expression system: Escherichia coli