7ls9

Electron Microscopy
3.42Å resolution

Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-210226 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1288 amino acids
Theoretical weight: 142.4 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:
1-57 Fab heavy chain Chains: D, E, H
Molecule details ›
Chains: D, E, H
Length: 244 amino acids
Theoretical weight: 26.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
1-57 Fab light chain Chains: F, G, L
Molecule details ›
Chains: F, G, L
Length: 215 amino acids
Theoretical weight: 23.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.42Å
Relevant EMDB volumes: EMD-23506
Expression system: Homo sapiens