7lin

X-ray diffraction
1.44Å resolution

X-ray structure of SPOP MATH domain (D140G) in complex with a 53BP1 peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Speckle-type POZ protein Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43791 (Residues: 29-166; Coverage: 37%)
Gene name: SPOP
Sequence domains: MATH domain
TP53-binding protein 1 Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q12888 (Residues: 1636-1650; Coverage: 1%)
Gene name: TP53BP1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: C2221
Unit cell:
a: 43.657Å b: 90.724Å c: 92.819Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.167 0.186
Expression systems:
  • Escherichia coli
  • Not provided