7kmi

X-ray diffraction
1.73Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-209803 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
LY-CoV481 Fab heavy chain Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 23.56 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
LY-CoV481 Fab light chain Chain: B
Molecule details ›
Chain: B
Length: 213 amino acids
Theoretical weight: 22.94 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 205 amino acids
Theoretical weight: 23.17 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DTC2 (Residues: 329-527; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: C2
Unit cell:
a: 105.239Å b: 74.046Å c: 126.086Å
α: 90° β: 111.85° γ: 90°
R-values:
R R work R free
0.188 0.186 0.217
Expression system: Cricetulus griseus