7k8n

X-ray diffraction
1.65Å resolution

Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
C102 Fab Heavy Chain Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 23.3 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
C102 Fab Light Chain Chain: B
Molecule details ›
Chain: B
Length: 214 amino acids
Theoretical weight: 23.31 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-1
Spacegroup: P6522
Unit cell:
a: 88.813Å b: 88.813Å c: 218.858Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 0.196 0.207
Expression system: Homo sapiens