X-ray diffraction
2.71Å resolution

Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 98 amino acids
Theoretical weight: 11.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
  • Canonical: A0A6B9UEV8 (Residues: 1-97; Coverage: 83%)
Sequence domains: Immunoglobulin domain
Rifin Chains: B, D
Molecule details ›
Chains: B, D
Length: 145 amino acids
Theoretical weight: 15.13 KDa
Source organism: Plasmodium falciparum NF54
Expression system: Homo sapiens
  • Canonical: Q8IJ06 (Residues: 184-328; Coverage: 41%)
Gene name: PF3D7_1040300

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 144.409Å b: 72.178Å c: 57.917Å
α: 90° β: 91.08° γ: 90°
R R work R free
0.244 0.24 0.281
Expression system: Homo sapiens