7jwp

X-ray diffraction
3Å resolution

Fab CJ11 in complex IL-18 peptide liberated by Caspase cleavage

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-211794 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fab CJ11 Heavy chain Chains: A, C, E, G, I, K, M, O
Molecule details ›
Chains: A, C, E, G, I, K, M, O
Length: 219 amino acids
Theoretical weight: 23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Fab CJ11 Light chain Chains: B, D, F, H, J, L, N, P
Molecule details ›
Chains: B, D, F, H, J, L, N, P
Length: 217 amino acids
Theoretical weight: 23.4 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
IL-18 peptide Chains: Q, R, S, T, U, V, W, X
Molecule details ›
Chains: Q, R, S, T, U, V, W, X
Length: 6 amino acids
Theoretical weight: 635 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P1
Unit cell:
a: 81.348Å b: 83.524Å c: 145.794Å
α: 107.24° β: 106.53° γ: 89.98°
R-values:
R R work R free
0.251 0.235 0.26
Expression systems:
  • Homo sapiens
  • Not provided