› 7fzr

X-ray diffraction
1.12Å resolution

Crystal Structure of human FABP4 in complex with 4-hydroxy-6-(2-naphthalen-1-ylethyl)pyran-2-one

Released:
DOI: 10.2210/pdb7fzr/pdb
PDB entry 7fzr coloured by chain, front view.
PDB entry 7fzr coloured by chain, side view.
PDB entry 7fzr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ehler A, Benz J, Obst U, Maurer M, Rudolph MG

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147213 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, adipocyte Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15090 (Residues: 1-132; Coverage: 100%)
Gene name: FABP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

3 bound ligands:
Ligand FMT 1 x FMT
Ligand SO4 2 x SO4
Ligand WHN 1 x WHN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 32.396Å b: 53.936Å c: 75.085Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.122 0.121 0.148
Expression system: Escherichia coli BL21(DE3)

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