› 7f4a

X-ray diffraction
2Å resolution

Crystal structure of Taf14 YEATS domain in complex with H3K9bz peptide

Released:
DOI: 10.2210/pdb7f4a/pdb
PDB entry 7f4a coloured by chain, front view.
PDB entry 7f4a coloured by chain, side view.
PDB entry 7f4a coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Global profiling of regulatory elements in the histone benzoylation pathway.
Wang D, Yan F, Wu P, Ge K, Li M, Li T, Gao Y, Peng C, Chen Y
Nat Commun 13 1369 (2022)
PMID: 35296687

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152814 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcription initiation factor TFIID subunit 14 Chain: A
Molecule details ›
Chain: A
Length: 136 amino acids
Theoretical weight: 15.64 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P35189 (Residues: 2-137; Coverage: 56%)
Gene names: ANC1, CST10, SWP29, TAF14, TAF30, TFG3, YPL129W
Sequence domains: YEATS family
Histone H3 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.04 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Not provided
UniProt:
  • Canonical: P61830 (Residues: 6-14; Coverage: 7%)
Gene names: HHT1, HHT2, N2749, SIN2, YBR010W, YBR0201, YNL031C

Ligands and Environments

No bound ligands
1 modified residue:
Ligand LBZ 1 x LBZ

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P65
Unit cell:
a: 113.786Å b: 113.786Å c: 26.62Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.176 0.204
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

3 review citations

Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications.
Zhong et al. (2023)
2 more