› 7dpx

X-ray diffraction
2Å resolution

Crystal structure of the SRCR domain of human SCARA1/CD204

Released:
DOI: 10.2210/pdb7dpx/pdb
PDB entry 7dpx coloured by chain, front view.
PDB entry 7dpx coloured by chain, side view.
PDB entry 7dpx coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Recognition of lipoproteins by scavenger receptor class A members.
Cheng C, Zheng E, Yu B, Zhang Z, Wang Y, Liu Y, He Y
J Biol Chem 297 100948 (2021)
PMID: 34252459

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149416 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Macrophage scavenger receptor types I and II Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.44 KDa
Source organism: Homo sapiens
Expression system: Insect cell expression vector pTIE1
UniProt:
  • Canonical: P21757 (Residues: 349-451; Coverage: 23%)
Gene names: MSR1, SCARA1
Sequence domains: Scavenger receptor cysteine-rich domain

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P212121
Unit cell:
a: 37.031Å b: 57.086Å c: 62.223Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.208 0.252
Expression system: Insect cell expression vector pTIE1

Quick links

Citations

2 review citations

Atherosclerosis and Inflammation: Insights from the Theory of General Pathological Processes.
Gusev et al. (2023)
1 more

3 mentions without citation

Recognition of lipoproteins by scavenger receptor class A members.
Cheng et al. (2021)
2 more