7cr4

Electron Microscopy
3.9Å resolution

human KCNQ2-CaM in complex with ztz240

Released:
Source organism: Homo sapiens
Related structures: EMD-30447

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium voltage-gated channel subfamily KQT member 2 Chains: A, B, D, F
Molecule details ›
Chains: A, B, D, F
Length: 656 amino acids
Theoretical weight: 73.63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O43526 (Residues: 64-702; Coverage: 73%)
Gene name: KCNQ2
Sequence domains:
Calmodulin-3 Chains: C, E, G, H
Molecule details ›
Chains: C, E, G, H
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P0DP25 (Residues: 1-149; Coverage: 100%)
Gene names: CALM3, CALML2, CAM3, CAMC, CAMIII
Sequence domains: EF-hand domain pair

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-30447
Expression system: Homo sapiens