7che

X-ray diffraction
3.42Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
BD-236 Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 223 amino acids
Theoretical weight: 23.33 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
BD-236 Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chain: R
Molecule details ›
Chain: R
Length: 223 amino acids
Theoretical weight: 25.12 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
BD-368-2 Fab heavy chain Chain: A
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 24.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
BD-368-2 Fab light chain Chain: B
Molecule details ›
Chain: B
Length: 219 amino acids
Theoretical weight: 23.9 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 100.016Å b: 114.296Å c: 116.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.225 0.239
Expression systems:
  • Homo sapiens
  • Trichoplusia ni