› 7cga

X-ray diffraction
3.15Å resolution

Crystal structure of human unphosphorylated p38gamma

Released:
DOI: 10.2210/pdb7cga/pdb
PDB entry 7cga coloured by chain, front view.
PDB entry 7cga coloured by chain, side view.
PDB entry 7cga coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lee CC, Hsu SF, Chen KE, Wang AHJ, Meng TC

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156873 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 12 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 348 amino acids
Theoretical weight: 39.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53778 (Residues: 9-353; Coverage: 94%)
Gene names: ERK6, MAPK12, SAPK3
Sequence domains: Protein kinase domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL15A1
Spacegroup: P6322
Unit cell:
a: 183.631Å b: 183.631Å c: 294.242Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.163 0.16 0.218
Expression system: Escherichia coli

Quick links