› › Function and Biology

SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab

Source organisms:
Biochemical function: not assigned
Biological process: endocytosis involved in viral entry into host cell
Cellular component: virion membrane

Quick links

GO terms

Sequence families

Pfam Protein families (Pfam)
PF01601
Domain description: Coronavirus spike glycoprotein S2
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7cai contains 3 copies of Pfam domain PF01601 ( Coronavirus spike glycoprotein S2) in Spike glycoprotein. Showing 1 copy in chain A.

PF19209
Domain description: Coronavirus spike glycoprotein S1, C-terminal
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7cai contains 3 copies of Pfam domain PF19209 ( Coronavirus spike glycoprotein S1, C-terminal) in Spike glycoprotein. Showing 1 copy in chain A.

PF09408
Domain description: Betacoronavirus spike glycoprotein S1, receptor binding
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7cai contains 3 copies of Pfam domain PF09408 ( Betacoronavirus spike glycoprotein S1, receptor binding) in Spike glycoprotein. Showing 1 copy in chain A.

PF16451
Domain description: Betacoronavirus-like spike glycoprotein S1, N-terminal
Occurring in:
  1. Spike glycoprotein
The deposited structure of PDB entry 7cai contains 3 copies of Pfam domain PF16451 ( Betacoronavirus-like spike glycoprotein S1, N-terminal) in Spike glycoprotein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR043473
Domain description: Spike glycoprotein S2 superfamily, coronavirus
Occurring in:
  1. Spike glycoprotein
IPR018548
Domain description: Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus
Occurring in:
  1. Spike glycoprotein
IPR032500
Domain description: Spike glycoprotein S1, N-terminal domain, betacoronavirus-like
Occurring in:
  1. Spike glycoprotein
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Light chain of H014 Fab
  2. Heavy chain of H014 Fab
IPR044874
Domain description: Spike glycoprotein S2, coronavirus, heptad repeat 2
Occurring in:
  1. Spike glycoprotein
IPR044873
Domain description: Spike glycoprotein S2, coronavirus, heptad repeat 1
Occurring in:
  1. Spike glycoprotein
IPR002552
Domain description: Spike glycoprotein S2, coronavirus
Occurring in:
  1. Spike glycoprotein
IPR043607
Domain description: Coronavirus spike glycoprotein S1, C-terminal
Occurring in:
  1. Spike glycoprotein
IPR036326
Domain description: Spike S1 subunit, receptor binding domain superfamily, betacoronavirus
Occurring in:
  1. Spike glycoprotein
IPR044366
Domain description: Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2
Occurring in:
  1. Spike glycoprotein
IPR043002
Domain description: Spike glycoprotein, N-terminal domain superfamily
Occurring in:
  1. Spike glycoprotein
IPR044341
Domain description: Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like
Occurring in:
  1. Spike glycoprotein
IPR042578
Domain description: Spike glycoprotein, betacoronavirus
Occurring in:
  1. Spike glycoprotein

Quick links