X-ray diffraction
2Å resolution

Crystal structure of an integral membrane steroid 5-alpha-reductase PbSRD5A


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
S5A_REDUCTASE domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 29.06 KDa
Source organism: Proteobacteria bacterium
Expression system: Spodoptera frugiperda
  • Canonical: A0A3A0FWV3 (Residues: 1-253; Coverage: 100%)
Gene name: DCC71_03205
Sequence domains: 3-oxo-5-alpha-steroid 4-dehydrogenase

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: C2221
Unit cell:
a: 52.192Å b: 104.266Å c: 123.046Å
α: 90° β: 90° γ: 90°
R R work R free
0.197 0.193 0.233
Expression system: Spodoptera frugiperda