Function and Biology

Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.

Source organism: Schizosaccharomyces pombe 972h-
Biochemical function: metal ion binding
Biological process: mRNA cis splicing, via spliceosome
Cellular component: U2AF complex

Sequence families

Pfam Protein families (Pfam)
PF00642
Domain description: Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
The deposited structure of PDB entry 7c06 contains 18 copies of Pfam domain PF00642 (Zinc finger C-x8-C-x5-C-x3-H type (and similar)) in Splicing factor U2AF 23 kDa subunit. Showing 2 copies in chain A.

PF00076
Domain description: RNA recognition motif
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
The deposited structure of PDB entry 7c06 contains 9 copies of Pfam domain PF00076 (RNA recognition motif) in Splicing factor U2AF 23 kDa subunit. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR009145
Domain description: U2 auxiliary factor small subunit
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
IPR000571
Domain description: Zinc finger, CCCH-type
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
IPR000504
Domain description: RNA recognition motif domain
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
IPR035979
Domain description: RNA-binding domain superfamily
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
IPR003954
Domain description: RNA recognition motif domain, eukaryote
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit
IPR012677
Domain description: Nucleotide-binding alpha-beta plait domain superfamily
Occurring in:
  1. Splicing factor U2AF 23 kDa subunit