7bm4

X-ray diffraction
1.6Å resolution

Crystal structure of alpha Carbonic anhydrase from Schistosoma mansoni bound to 1-(4-fluorophenyl)-3-(4-sulphamoylphenyl)selenourea

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase Chains: A, B
Molecule details ›
Chains: A, B
Length: 332 amino acids
Theoretical weight: 37.93 KDa
Source organism: Schistosoma mansoni
Expression system: Cricetulus griseus
UniProt:
  • Canonical: A0A3Q0KSG2 (Residues: 21-298; Coverage: 92%)
Sequence domains: Eukaryotic-type carbonic anhydrase

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 11.2C
Spacegroup: P3221
Unit cell:
a: 102.896Å b: 102.896Å c: 132.225Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.167 0.166 0.194
Expression system: Cricetulus griseus