› 7bdo

X-ray diffraction
2.7Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155650 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 14 Chain: A
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 41.4 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P47811 (Residues: 1-360; Coverage: 100%)
Gene names: Crk1, Csbp1, Csbp2, Mapk14
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:
Ligand TBK 1 x TBK
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 65.458Å b: 72.549Å c: 76.259Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.239 0.287
Expression system: Escherichia coli

Quick links

Citations

3 mentions without citation

In silico activity and ADMET profiling of phytochemicals from Ethiopian indigenous aloes using pharmacophore models.
Bultum et al. (2022)
2 more