7b4v

X-ray diffraction
1.4Å resolution

Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Broadly neutralizing DARPin bnD.2 Chains: A, C
Molecule details ›
Chains: A, C
Length: 132 amino acids
Theoretical weight: 13.74 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505) Chains: B, D
Molecule details ›
Chains: B, D
Length: 15 amino acids
Theoretical weight: 1.6 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 50.63Å b: 69.34Å c: 69.92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.196
Expression systems:
  • Escherichia coli
  • Not provided