7az3

Hybrid

Function and Biology Details

Reaction catalysed:
D-glyceraldehyde 3-phosphate = glycerone phosphate
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Triosephosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 251 amino acids
Theoretical weight: 27.21 KDa
Source organism: Leishmania mexicana
Expression system: Escherichia coli
UniProt:
  • Canonical: P48499 (Residues: 1-251; Coverage: 100%)
Sequence domains: Triosephosphate isomerase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Experimental Method: Neutron Diffraction, X-ray diffraction
X-ray source: ESRF BEAMLINE BM30A, ILL BEAMLINE LADI III
Spacegroup: C2
Unit cell:
a: 98.341Å b: 52.365Å c: 58.463Å
α: 90° β: 118.03° γ: 90°
R-values:
R R work R free
0.14 0.14 0.153
Expression system: Escherichia coli