7aql

X-ray diffraction
1.8Å resolution

Crystal Structure of an Anti-Plasminogen Activator Inhibitor-1 (PAI-1) scFv antibody fragment (scFv-33H1F7)

Released:
Source organism: Mus musculus
Entry authors: Sillen M, Weeks SD, Strelkov SV, Declerck PJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214316 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
scFv-33H1F7 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 242 amino acids
Theoretical weight: 25.95 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2
Unit cell:
a: 190.398Å b: 55.577Å c: 102.493Å
α: 90° β: 90.28° γ: 90°
R-values:
R R work R free
0.187 0.186 0.223
Expression system: Escherichia coli BL21(DE3)