7aqk

Electron Microscopy
9Å resolution

Model of the actin filament Arp2/3 complex branch junction in cells

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octadecamer (preferred)
Entry contents:
8 distinct polypeptide molecules
Macromolecules (8 distinct):
Actin-related protein 2 Chain: b
Molecule details ›
Chain: b
Length: 394 amino acids
Theoretical weight: 44.82 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P61161 (Residues: 1-394; Coverage: 100%)
Gene names: Actr2, Arp2
Sequence domains: Actin
Actin-related protein 3 Chain: a
Molecule details ›
Chain: a
Length: 418 amino acids
Theoretical weight: 47.43 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q99JY9 (Residues: 1-418; Coverage: 100%)
Gene names: Actr3, Arp3
Sequence domains: Actin
Actin-related protein 2/3 complex subunit 1B Chain: c
Molecule details ›
Chain: c
Length: 372 amino acids
Theoretical weight: 41.02 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9WV32 (Residues: 1-371; Coverage: 100%)
Gene name: Arpc1b
Sequence domains: WD domain, G-beta repeat
Actin-related protein 2/3 complex subunit 2 Chain: d
Molecule details ›
Chain: d
Length: 300 amino acids
Theoretical weight: 34.4 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CVB6 (Residues: 1-300; Coverage: 100%)
Gene name: Arpc2
Sequence domains: Arp2/3 complex, 34 kD subunit p34-Arc
Actin-related protein 2/3 complex subunit 3 Chain: e
Molecule details ›
Chain: e
Length: 178 amino acids
Theoretical weight: 20.57 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9JM76 (Residues: 1-178; Coverage: 100%)
Gene name: Arpc3
Sequence domains: ARP2/3 complex ARPC3 (21 kDa) subunit
Actin-related protein 2/3 complex subunit 4 Chain: f
Molecule details ›
Chain: f
Length: 168 amino acids
Theoretical weight: 19.7 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P59999 (Residues: 1-168; Coverage: 100%)
Gene names: Arc20, Arpc4
Sequence domains: ARP2/3 complex 20 kDa subunit (ARPC4)
Actin-related protein 2/3 complex subunit 5 Chain: g
Molecule details ›
Chain: g
Length: 151 amino acids
Theoretical weight: 16.3 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q9CPW4 (Residues: 1-151; Coverage: 100%)
Gene name: Arpc5
Sequence domains: ARP2/3 complex 16 kDa subunit (p16-Arc)
Actin, alpha skeletal muscle Chains: h, i, j, k, l, m, n, o, p, q, r
Molecule details ›
Chains: h, i, j, k, l, m, n, o, p, q, r
Length: 377 amino acids
Theoretical weight: 42.1 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P68134 (Residues: 1-377; Coverage: 100%)
Gene names: Acta, Acta1
Sequence domains: Actin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-11869