› 7afx

X-ray diffraction
1.64Å resolution

Crystal structure of the metallo-beta-lactamase VIM2 with 139

Released:
DOI: 10.2210/pdb7afx/pdb
PDB entry 7afx coloured by chain, front view.
PDB entry 7afx coloured by chain, side view.
PDB entry 7afx coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Entry authors: Brem J, Schofield CJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191748 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallo-beta-lactamase type 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 242 amino acids
Theoretical weight: 25.69 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K2N0 (Residues: 27-266; Coverage: 98%)
Gene names: PAERUG_P19_London_7_VIM_2_05_10_01672, bla vim-2, blaVIM-2, blm
Sequence domains: Metallo-beta-lactamase superfamily

Ligands and Environments

3 bound ligands:
Ligand ZN 6 x ZN
Ligand R9K 2 x R9K
Ligand FMT 6 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 103.251Å b: 79.066Å c: 67.951Å
α: 90° β: 130.37° γ: 90°
R-values:
R R work R free
0.161 0.16 0.181
Expression system: Escherichia coli

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