Assemblies
Assembly Name:
SARS-CoV-2 uncleaved Spike protein complex and Processed angiotensin-converting enzyme 2
Multimeric state:
hetero tetramer
Accessible surface area:
173408.39 Å2
Buried surface area:
26684.4 Å2
Dissociation area:
921.15
Å2
Dissociation energy (ΔGdiss):
-5.41
kcal/mol
Dissociation entropy (TΔSdiss):
15.83
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-144662
Macromolecules
Chains: A, B, C
Length: 1287 amino acids
Theoretical weight: 142.41 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
Pfam:
Length: 1287 amino acids
Theoretical weight: 142.41 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
- Canonical:
P0DTC2 (Residues: 1-1208; Coverage: 95%)
Pfam:
- Betacoronavirus-like spike glycoprotein S1, N-terminal
- Betacoronavirus spike glycoprotein S1, receptor binding
- Coronavirus spike glycoprotein S1, C-terminal
- Coronavirus spike glycoprotein S2
- Spike glycoprotein, betacoronavirus
- Spike glycoprotein S1, N-terminal domain, betacoronavirus-like
- Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like
- Spike glycoprotein, N-terminal domain superfamily
- Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2
- Spike S1 subunit, receptor binding domain superfamily, betacoronavirus
- Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus
- Coronavirus spike glycoprotein S1, C-terminal
- Spike glycoprotein S2, coronavirus
- Spike glycoprotein S2, coronavirus, heptad repeat 1
- Spike glycoprotein S2 superfamily, coronavirus
- Spike glycoprotein S2, coronavirus, heptad repeat 2
- Fibritin C-terminal
Chain: D
Length: 654 amino acids
Theoretical weight: 75.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam: Angiotensin-converting enzyme
InterPro: Peptidase M2, peptidyl-dipeptidase A
Length: 654 amino acids
Theoretical weight: 75.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q9BYF1 (Residues: 19-615; Coverage: 76%)
Pfam: Angiotensin-converting enzyme
InterPro: Peptidase M2, peptidyl-dipeptidase A
