› 7a93

Electron Microscopy
5.9Å resolution

SARS-CoV-2 Spike Glycoprotein with 2 RBDs Erect

Released:
DOI: 10.2210/pdb7a93/pdb
PDB 7a93 coloured by chain and viewed from the front.
PDB 7a93 coloured by chain and viewed from the side.
PDB 7a93 coloured by chain and viewed from the top.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Benton DJ, Wrobel AG, Xu P, Roustan C, Martin SR, Rosenthal PB, Skehel JJ, Gamblin SJ
Nature 588 327-330 (2020)
PMID: 32942285
Related structures: EMD-11683

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1287 amino acids
Theoretical weight: 142.41 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.9Å
Relevant EMDB volumes: EMD-11683
Expression system: Homo sapiens

Quick links

Citations

4 review citations

Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy.
Cruz-Teran et al. (2021)
3 more