› 7a5m

X-ray diffraction
0.78Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167982 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein enabled homolog Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8N8S7 (Residues: 1-111; Coverage: 19%)
Gene names: ENAH, MENA
Sequence domains: WH1 domain
Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe Chains: B, C
Molecule details ›
Chains: B, C
Length: 4 amino acids
Theoretical weight: 706 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NO3 1 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: C2221
Unit cell:
a: 35.15Å b: 61.36Å c: 88.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.12 0.119 0.14
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

4 review citations

Migration and homeostasis of regulatory T cells in rheumatoid arthritis.
Kotschenreuther et al. (2022)
3 more

1 mention without citation

An amino-domino model described by a cross-peptide-bond Ramachandran plot defines amino acid pairs as local structural units.
Rosenberg et al. (2023)