7a41

X-ray diffraction
2.13Å resolution

MALT1 in complex with a NVS-MALT1 chemical probe

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 404 amino acids
Theoretical weight: 45.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UDY8 (Residues: 329-728; Coverage: 49%)
Gene names: MALT1, MLT
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 64.21Å b: 106.57Å c: 73.68Å
α: 90° β: 111.84° γ: 90°
R-values:
R R work R free
0.202 0.2 0.23
Expression system: Escherichia coli BL21(DE3)